Eli Lilly is a drug firm with a focus on neuroscience, cardiometabolic, cancer, and immunology. Lilly's key products include Verzenio for cancer; Mounjaro, Zepbound, Jardiance, Trulicity, Humalog, and Humulin for cardiometabolic; and Taltz and Olumiant for immunology.
The chart shows the growth of an initial investment of $10,000 in Eli Lilly & Co., comparing it to the performance of the S&P 500 index. All prices have been adjusted for splits and dividends.
Returns By Period
Eli Lilly & Co. (LLY) has returned -13.08% so far this year and 34.05% over the past 12 months. Looking at the last ten years, LLY has achieved an annualized return of 28.96%, outperforming the Benchmark (SPY), which averaged 12.23% per year.
LLY
1M-5.50%
6M11.39%
YTD-13.08%
1Y34.05%
5Y38.52%
10Y28.96%
Benchmark (SPY)
1M-3.85%
6M-2.35%
YTD-4.36%
1Y34.06%
5Y9.80%
10Y12.23%
Monthly Returns
The table below presents the monthly returns of Eli Lilly & Co. (LLY) with color gradation from worst to best to easily spot seasonal factors.
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
2026
-3.65%
1.39%
-11.95%
0.94%
2025
3.91%
14.47%
-9.52%
9.82%
-12.60%
6.42%
-5.06%
-1.91%
4.81%
13.04%
24.11%
0.03%
2024
11.23%
16.43%
1.16%
0.66%
5.88%
9.90%
-11.79%
15.16%
-7.50%
-6.65%
-3.94%
-3.27%
2023
-6.04%
-9.21%
10.78%
15.33%
8.11%
9.00%
-2.51%
21.71%
-3.45%
3.34%
6.49%
-1.48%
2022
-10.58%
1.17%
15.68%
2.09%
7.63%
3.44%
1.79%
-8.02%
7.43%
11.07%
7.30%
-2.39%
2021
23.04%
-2.18%
-9.21%
-2.17%
9.15%
14.58%
6.10%
5.11%
-10.63%
10.29%
-2.77%
10.74%
2020
5.97%
-10.25%
8.60%
15.40%
-0.50%
6.29%
-8.54%
-2.89%
-0.40%
-12.05%
9.89%
15.10%
2019
4.42%
4.96%
1.97%
-10.46%
-0.95%
-4.93%
-2.12%
3.62%
-0.63%
1.80%
2.88%
11.84%
2018
-3.56%
-5.54%
0.40%
5.45%
5.40%
0.15%
16.17%
7.00%
1.90%
0.72%
9.10%
-2.46%
2017
4.18%
6.30%
0.80%
-2.46%
-3.07%
3.39%
0.30%
-1.89%
4.91%
-4.48%
3.01%
-0.61%
2016
5.49%
-1.21%
5.14%
5.07%
-6.35%
3.23%
-7.70%
-9.06%
9.30%
Performance Indicators
The charts below present risk-adjusted performance metrics for Eli Lilly & Co. (LLY) and compare them to a Benchmark (SPY). These indicators evaluate an investment's returns against its associated risks.
Sharpe ratio
Sortino ratio
Omega ratio
Calmar ratio
Martin ratio
sharpe ratio
The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.
These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns.
The chart below shows the rolling Sharpe ratio of LLY compared to the benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.
Volatility Chart
The current Eli Lilly & Co. volatility is 2.13%, representing the standart deviation of percentage change in the investments's value, either up or down over the past month. The chart below shows the rolling one-month volatility.
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. It shows the maximum percentage drop from a peak to a trough over a specified period, indicating the risk of significant losses. Although chart shows positive values, it represents the percentage drop from the peak, so a value of 10% means the portfolio has dropped 10% from its highest point.
Income Statement
The income statement provides a summary of a company's revenues, expenses, and profits over a specific period. It shows how much money the company earned (revenues) and how much it spent (expenses), leading to the net income or profit. This statement is crucial for understanding a company's financial performance and profitability.
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015
2014
2013
2012
2011
Liabilities And Equity (USD)
112.48B
78.71B
64.01B
49.49B
48.81B
46.63B
39.29B
43.91B
44.98B
38.81B
35.57B
37.18B
35.25B
34.40B
33.66B
Equity Attributable To Parent (USD)
26.54B
14.19B
10.77B
10.65B
8.98B
5.64B
2.61B
9.83B
11.59B
14.01B
14.57B
15.37B
17.63B
14.77B
13.54B
Equity Attributable To Noncontrolling Interest (USD)
Novo Nordisk announced a new subscription model for Wegovy offering 3, 6, or 12-month prescriptions at discounted prices to expand market reach in the weight-loss drug space. Despite losing market leadership to Eli Lilly, the company's pricing strategy could help penetrate the underpenetrated obesity market, where only 12% of Americans currently use GLP-1 drugs despite 40-70% obesity rates. Novo Nordisk stock trades at an attractive valuation of 11x forward earnings compared to healthcare average of 17.3x.
The Motley Fool•Prosper Junior Bakiny
AI Insight
Eli Lilly is acknowledged as the current market leader in the anti-obesity space, having taken the lead from Novo Nordisk over the past two years. However, the article suggests the competitive advantage may be temporary as Eli Lilly will likely adjust prices in response to Novo Nordisk's moves, indicating a competitive but not fundamentally advantageous position.
Viking Therapeutics, a clinical-stage biotech company, is developing VK2735, a dual GLP-1/GIP agonist for weight management currently in phase 3 trials. The company could potentially capture significant market share in the projected $100+ billion weight-loss market if VK2735 demonstrates efficacy comparable to Eli Lilly's Zepbound. However, the company faces substantial risks including clinical setbacks, intense competition, and the historical difficulty most biotechs face in achieving sustained success.
The Motley Fool•Prosper Junior Bakiny
AI Insight
Eli Lilly's Zepbound is currently the leading weight-loss medicine with strong 2025 sales of $13.5 billion, establishing it as the market standard. The company has demonstrated commercial success in the rapidly growing obesity drug market.
Major M&A activity dominates the market with McCormick merging with Unilever's Foods business in a $29.1 billion deal, Sysco acquiring Jetro Restaurant Depot for $29 billion, and Eli Lilly acquiring Centessa Pharmaceuticals for $7.8 billion. Meanwhile, QVC faces financial distress and is considering Chapter 11 bankruptcy, while several other companies including IO Biotech and Lipella Pharmaceuticals have filed for bankruptcy.
Benzinga•Caroline Ryan
AI Insight
Acquiring Centessa Pharmaceuticals for $7.8 billion to enhance revenue growth and expand immunology and rare disease portfolio
U.S. stock markets opened sharply lower on April 2, 2026, amid Iran conflict concerns and Tesla's disappointing delivery report, but recovered to near breakeven by midday. Oil prices surged 10% following Trump's Wednesday address, though reports of Iran-Oman negotiations on Strait of Hormuz traffic helped stabilize stocks. Tesla's first-quarter deliveries fell short of expectations, while healthcare stocks declined on tariff concerns.
The Motley Fool•Anders Bylund
AI Insight
Healthcare sector declined approximately 2% due to reports of potential Trump administration tariffs of up to 100% on imported pharmaceuticals.
Eli Lilly commits over $10 billion to two major strategic initiatives: a $2.75 billion expanded partnership with InSilico Medicine to leverage AI for drug discovery, and a $6.3-7.8 billion acquisition of Centessa Pharmaceuticals to enter the sleep-wake disorders market. These moves aim to modernize R&D processes, diversify revenue beyond its GLP-1 franchise, and support the company's premium valuation.
Investing.com•Jeffrey Neal Johnson
AI Insight
The company is making substantial strategic investments to modernize drug discovery through AI and diversify its pipeline beyond blockbuster GLP-1 drugs. These forward-thinking moves address long-term risks like patent cliffs and demonstrate management's commitment to sustained growth, supporting its premium valuation.
Merck announced its acquisition of Terns Pharmaceutical for $6.7 billion to bolster its cancer treatment pipeline with TERN-701, an oral BCR-ABL1 inhibitor for chronic myeloid leukemia. This marks the third multi-billion-dollar acquisition in a year, reinforcing Merck's M&A strategy. The company has a strong earnings track record, forecasts over $70 billion in commercial opportunity by mid-2030s, maintains a 73% gross margin, and has increased dividends for 14 consecutive years.
Investing.com•Jessica Mitacek
AI Insight
Mentioned only as a market cap comparison point ($830 billion), indicating it is the largest pharmaceutical company by market cap. No specific news or developments regarding the company are discussed in the article.
The Trump administration is preparing to announce 100% tariffs on pharmaceutical companies that haven't secured pricing deals with the White House, potentially as soon as Thursday. The tariffs stem from a Section 232 investigation citing national security grounds. Major drugmakers including Pfizer, Eli Lilly, AstraZeneca, Novo Nordisk, and Johnson & Johnson have already secured three-year reprieves by agreeing to most-favored-nation pricing. The tariff threat is part of a broader pricing strategy that includes the TrumpRx.gov platform for comparing discounted drug prices.
Benzinga•Tanya Rawat
AI Insight
Secured a three-year reprieve through most-favored-nation pricing agreement, protecting from tariff threat
While Eli Lilly dominates the weight loss drug market with Mounjaro and Zepbound generating $11 billion in the latest quarter, the company's next major growth driver may be artificial intelligence for drug discovery. Lilly is making significant investments in AI through partnerships with Nvidia and Insilico Medicine, aiming to accelerate the drug development process and bring new blockbuster drugs to market across multiple therapeutic areas.
The Motley Fool•Adria Cimino
AI Insight
The company is positioned as a market leader in obesity drugs with strong revenue growth (43% increase), and is making strategic investments in AI-driven drug discovery that could accelerate its entire pipeline and create multiple future blockbuster drugs across various therapeutic areas.
Eli Lilly's stock surged nearly 4% after the FDA approved Foundayo, its first daily oral weight-loss pill. The drug will compete with Novo Nordisk's Wegovy pill, with pricing starting at $149 monthly. While Wegovy showed higher weight-loss results in trials, Eli Lilly's larger resources and marketing capabilities are expected to drive significant adoption of Foundayo.
The Motley Fool•Eric Volkman
AI Insight
FDA approval of Foundayo, a convenient daily oral weight-loss pill, represents a significant product expansion. The stock gained 3.78% on the news, and the company's substantial resources position it well to capture market share in the growing obesity treatment market.
U.S. markets rallied on April 1, 2026, driven by easing Iran war concerns and falling oil prices. The S&P 500 rose 0.72%, Nasdaq climbed 1.16%, and the Dow added 0.48%. Semiconductor stocks surged while energy stocks declined sharply. Nike tumbled 15% on disappointing earnings, while Eli Lilly jumped on FDA approval of its obesity pill. Despite today's gains, the S&P 500 remains down 4% year-to-date.
The Motley Fool•Emma Newbery
AI Insight
Stock jumped 3.84% following FDA approval of its new obesity pill